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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c15b79beb1bfc51eb50c33ea08f9998c951cc4e641aa9e7b5d5b420fbb18366b' 
  AND token = 'pU4L5yA3IPzXubjovNMK7T+PbAQM52RbWnZ1U0yfTEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}