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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bd72f0ece4628cb240dcf4ea10b73e207929aa8beea782db34c92e0905dbd11' 
  AND token = 'A6ui9pzg/A4mq/XIBFk5itOcrcjWLt9/8+/xV6GSD1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}