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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '921cbd9ef1511eceeb55c382a2c74d840ac66b59bf72059e321d04a1b191d260' 
  AND token = 'AoC4q6Zey1m4u6g89N2V9Cjm5IHPo28lNL+DDc8c8FM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}