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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58eb197f82a146f9627450125b1c57c4eddf7ebf6d8fb020614df7ba3d9a0b26' 
  AND token = '/J0PwHCQRVyhBOBoJPcFfNMxH9s0dwc9tFwPSijhSPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}