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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f57e729122cf31d13107a01b2ae89fc875bc8d929f97e117f577f916895fd57' 
  AND token = 'VHE82WMS0Cq56wdUQPI9/uCih4J4+aKT2/xCZMpip0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}