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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65a21f7c1292577c19e04ebbd95b82463af8d0194a5d0fe3d729b92d05ccd24e' 
  AND token = 'cQ5phpOPiG2KiWz4+QHo0U8JeR4ai6pYvfMeXB5Jjfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}