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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f022502cbc8a2a228e5b91c75be51d284f3449d61307024d6ffd27f1295b5b88' 
  AND token = 'R2as0FnzF07laeZaeI2zJtcJT+cnEzOQYw/5qDU/sPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}