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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '603554b8dc07eab9f3d1f86ce8082cd438917b1982ad5b25433de2251df3ee87' 
  AND token = 'p1UQNKrKNJDUBicv6h4pdFm6vcEY/46hkDLC4Hf1SC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}