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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '054b559bbf21036b17180da3e70db9b9815a44a2b7bea7da05ffff9e30ea5ebe' 
  AND token = 'QFWuNF0XukTEB8qUIHuBSt1qHbj3FICWTAm7HTAb8ts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}