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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ab609475f975590d2def833a7ef75945c7c5f2fa9d7d196b8f893c733af3367' 
  AND token = 'Sts3hrCvoDPaHFHFBxUJdxJS7N0yh7SRk/eXZQBcSsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}