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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26d167cc1d9de72682c9bd18191b644d43fe76369b4c0c12152055d23bb493c5' 
  AND token = '1oVsQAFEaucTn+2PzekUTVoMLC0azgBt37qaI2u+4oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}