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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ef0d2ec27f17c3c26daf57c088517e82e62affef688ab6e3d6f2c8cd6c2c215' 
  AND token = 'X3CSJWIHj+sPiPF0LKbz3Rn03WScMMJkpF+bL5nbpm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}