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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a957c408a266e8ec91eb093c807490fd41a915ff5a0ee8fe0eb44bc45245221' 
  AND token = 'E5ijG0J4EH+rqdhsiUn/sp50F1N16fBG1A+IdSNQQhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}