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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63649d2f572a8763de7821d499617ad144dbe12d868c11bea19a312a1529b667' 
  AND token = '49ADWp78C8r6WoVK/OTSTf3eE8mNTXpF815iTHTG7XA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}