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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6cfbebb3fdd248d249cb58f7843aee5f22fd1452491e0cf3358b0c57783b6c9' 
  AND token = 'pR/6++ukpIH3teehVlHQ88Sn68E1TUKmUQI+H7XixAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}