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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c13cde22e2403cad2ef1680db136198b0484c7b6dfa4bee32d30e00e0eb3706' 
  AND token = 'SFO9teXUBvwGjIFV8zFh1ID2RJKJ3BjJ/HuktRmXTww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}