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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a61f86ae369260ad684c47d6b38e33a41b0a85ce073a615882d340971aa99cbe' 
  AND token = 'M/8S/pS0WTs7EN4+q/68sZ/eeUYTXW4ao9VQQkF8nwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}