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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75ade62498614b06ba94f226791fc38f6a8babbbb02fee4fcdc15469c239de9c' 
  AND token = 'yTZxQoDrs3Tzu0tHSUInkGdOnUYe7aXAV7t2dqkyZCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}