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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecc62fab9a6d69202c682fd1ee0a88c66b64aff7769dce7a437af15cf34c6b67' 
  AND token = 'tO7MQCqmPvQhOGLVnTCA0JZxPGL9QPl6JrVDz8nrCpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}