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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f88945e603ee68312b2e73dddd5ba968411808d7518451393a1637b37cea37ca' 
  AND token = '6+cxt8ybsvW+x9mTgqAZj3+Q26RCdZnsn3P7MzR/lBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}