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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5c77172125c73d6962b62142a191204640050f04dd1b62ce52a2bd871d5a70d' 
  AND token = 'C4Quno6m4eUr36MxMdDAYgv0cwW6h8y+nucbL2WydYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}