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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e566ca892afbfd01e2afb5b9618edeab1f791351c0d7e46b71f2ccb7f3389e20' 
  AND token = 'FJmB3V3nVV+Tzept/ovMrs+HCDYHIsO3a+Crac+rVF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}