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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a3d21066e2949a492eb6a392ec63d81450c8575e22925c76769df44dfcf8c7a' 
  AND token = 'jxWDd3220wdcgHi5GZanjwhXj8nbUT63nudQJUTFDxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}