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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fb6cbeecfe47fe857cb0b9560b0b8a11913197d778888297311631f45d61ef0' 
  AND token = 'fX2pdQ1Z1My45HSaADT1H59QAiNbDiKO8B2rqdd98Ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}