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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f345492509ac9e4d60d0266634625a65819911e2dcda56581414da4f5208ec8a' 
  AND token = '+7Vi+oDhVIEwyKwhH5suK6mAwUJvxOz86gcmnJV2KfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}