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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26b8b3a2f2de899617ef1d07257dcc2a2d4f47cfa7980422c520e52f4a2c7b89' 
  AND token = 'SZBnuEMoPC1hcIxdv62AttQTSLAy5ho+sMQc/nFuSS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}