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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ded1656edf7ed6c67a5d05f6f00ba78b2bc9db2f5edea5e093d61eff61ae077a' 
  AND token = 'fCRGEeQMpvjbGS95BR4NY+nRFXG0SPRvTD5U2RlEQRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}