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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cd17a5bf06bc625b108cc974bc10b4ffa9265a11939ea89434e3689cf94fa09' 
  AND token = '3nKhCmTE9hrA+KBGLvJ12cCWa+5tjK1br9cUqB/cby0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}