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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42849face50f110be06ee8f9c51a2682a1aaee2bb768ae4d974fd5075b570fbf' 
  AND token = '6Tp4uqhAWyYstALhvk+QlevLmbyCv7vUJ6xCVzESsvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}