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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7346141e5b6e14426c1024b611252a14e91c53d6712a3e84314162a316e0d89f' 
  AND token = 'WYda9wP8odLwrbAPnb47UxvlKWdEAFgmFkFWMgombrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}