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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52f543dc0f8cafa5c5e0b29f6e4494dc354def8d50f2e368e75e2020bb146bcd' 
  AND token = 'mcdj/S1FRolPrKgVQyecKmb3N4VJoDMUqy5IViQV4U4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}