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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '266adc4805bbd26994a1d054fea9f5b898aa81ca91f27f2879a11f3fe363a9f3' 
  AND token = '9xPMH/PK3SicOrwfnicD9rkNW3GODZ5GU6eh/A2arEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}