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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cdb9bd14b79a3915f2018fb607c3c3a4e4f8b1ab67091fe76c9e1950feb8b16' 
  AND token = 'EPbdjMtEa2ZnL6CU1uQU92/UJMurNxHe+lLjxsLT58w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}