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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ac016d3b681a0733dfc3ed44e8a8eec9a8fbd1e60a024d0ce9a0e9d0dff91a5' 
  AND token = 'ezNPoXqdqT0ZNn+TtOrkuyOvTuk/YEbL56IK/xpf5A0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}