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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3db437ba1fc0343d9ce2fe1a44df5d83cf2b548478f7f3ceccc053ada1f79fd2' 
  AND token = '7Q1SELzKBoSiDuRdLfEZOOfGH8Kj/3pIiZSbyBZeKZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}