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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05e35993fb6d580fb4f085290c1e1a713cf4d5f7d03c7a0d834c494b7c19dc3c' 
  AND token = 'hrS4v2Jfgxn8yNlamko5woDVZR0ISG4YKaVA0rCurF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}