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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4558a5b0282dcbf03d6422312c7d6d3ed6797dff2957ccd42e94c3df43d6718' 
  AND token = 'tOstkQ0/jG5O8T+TctmTvmSaaZxgNviLH5kxlrzMiaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}