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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ef1ebfd633cb8892129583d34ff9e9e63df38461da759d39235563f6b741f61' 
  AND token = '3SXdHnnVi05whUkhtx6jKBWC0aD4oSbP0UDkizX6+Bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}