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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d280daf7f30f254b411886c4562d1a48a01b8e1c75df2e2ecb459f38574ebb8' 
  AND token = '50beh7hM1NLvaMO0D89kWrylCxK0j5L4XRFslVLjYP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}