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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca7815af5e2606355705d95386e69a7762e8bda8a1ec30c7490e07345e4f6c90' 
  AND token = 'AfLSh9nxyvVvNM+BeLuuw0NCEvbmYITjxOsQnEQn1yI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}