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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c6e7b1e664707775308314e4fad25d4ebd6c4a782f8fd7fcde01529a3d7e5ff' 
  AND token = 'y50FnRcMmd2P0OZbtYFREu8I/MsjBR3jrwgqMQ/WBRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}