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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa2e8dc43c8142c6ce15a1f38a17d0be94e9e11c40f616dff151d3b0bc226d80' 
  AND token = 'xUqGBXdW6g2s7lW1xs4aE7c4laO8CJxRKxDUMQiSrFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}