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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a97a4e49f1312bae8f4284e1e96e3c74fc2bbab6ea44c573114bfaaa623c059' 
  AND token = 'lMUCUvFIoevo93LNk4kMeB1s2P/r1hiEz5Mzsa2uIXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}