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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef6de64f7fabca409107b5a747b5d9aa1df41b16d44be802daf941b3c4873fa5' 
  AND token = 'uF/zg6X3DWAwagejw/LzUC1xdnmqSBezdV3wRY1ilc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}