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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9089e1be68c0c71675dbf4b684fd89b7f3324df8b10ce1996ff2c79d343b652f' 
  AND token = 'fjjT6DLmgT7z0wtX0cW9vTVJevFCtemqiRnJAIXcNXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}