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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5484edf22a749a7c1c6826323eb33a6c25e458671b93678e825e1171b8a67c37' 
  AND token = 'Dwr/p23YGdsfDufo3nx/msAP5Slb7z74CpW5P54P6Yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}