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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43bab19750a61546eb1f2b9a388da4962a28cb2d69ccc385e1519a8f258c906c' 
  AND token = '7p71s25OicrxYaJKlVSNvKlq9xLXlpKx7aBH8GQXpJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}