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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db48f9e5f2a57123c5537e01577a59e092fe0b4538056f94c32f13636e286500' 
  AND token = 'SVMOpRCLUJ8dgntOAVhQQwhSf0pfwLocChngR6ADayA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}