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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a80b16cec3a5b6be95fa954d9bebbd5a95f74b87c1eccfd756cb8d96948a8144' 
  AND token = 'Ir4z0njBQIMemFRaAclUV2u0bXEjKr4Ha8JzlEuP12s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}