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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65606df3108775c2390e7bc4a0dd04b14c7d5e63e13effd76042dc0b91fdb2ff' 
  AND token = 'Iflv8SkH7ok1+mOXZTYtdMO7YZqFRLs0mIdd2saDeOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}